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Grapes and raisins are toxic to dogs!

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This entry was posted on 3/21/2007 6:47 PM and is filed under News and Events,Medical.

From the ASPCA's  Animal Poison Control Center, comes this warning on how toxic grapes and raisins are to dogs! Any amount - from over a pound of grapes to as little as a single serving of raisins can lead to acute renal (kidney) failure!  To read their full article: grapes and raisins prove toxic to dogs

The following is quoted directly from the ASPCA article:

Around 1989, the APCC began noticing a trend in dogs who had eaten grapes or raisins: Nearly all developed acute renal (kidney) failure. As more cases were reported, enough data was generated in the database to help veterinarians identify and treat dogs at risk. In all of the cases, the ingredients for potential acute renal failure were the same. Whether the ingested grapes were purchased fresh from grocery stores or grown in private yards didn't seem to matter, nor did the brand eaten. And the ingested amounts varied considerably, from over a pound of grapes to as little as a single serving of raisins. The cases weren't from any specific region, but instead came from across the United States.

The database showed that dogs who ate the grapes and raisins typically vomited within a few hours of ingestion. Most of the time, partially digested grapes and raisins could be seen in the vomit, fecal material, or both. At this point, some dogs would stop eating (anorexia), and develop diarrhea. The dogs often became quiet and lethargic, and showed signs of abdominal pain. These clinical signs lasted for several days — sometimes even weeks.

When medical care was sought, blood chemistry panels showed consistent patterns. Hypercalcemia (elevated blood calcium levels) was frequently present, as well as elevated levels of blood urea nitrogen, creatinine and phosphorous (substances that reflect kidney function). These chemistries began to increase anywhere from 24 hours to several days after the dogs ate the fruit. As the kidney damage developed, the dogs would produce little urine. When they could no longer produce urine, death occurred. In some cases, dogs who received timely veterinary care still had to be euthanized.

Why did the fruit cause the dogs to become ill? No one knows. Suspect grapes and raisins have been screened for various pesticides, heavy metals (such as zinc or lead), and mycotoxins (fungal contaminants) and so far, all results have come back negative. In the cases where the grapes were grown in private yards, owners confirmed that no insecticides, fertilizers or antifungals had been used on the fruit.

"Raisin" the Success Rate
Even though the exact cause of the renal failure is unknown, dogs who ingest grapes and raisins can be treated successfully to prevent its development. The first line of defense is decontamination. Inducing vomiting in recent ingestions and administering activated charcoal helps prevent absorption of potential toxins. Dogs should be hospitalized and placed on intravenous fluids for a minimum of 48 hours. A veterinarian should monitor blood chemistry daily for at least three days following the ingestion. If all blood work is normal after three days, it's unlikely that kidney failure will occur. If a dog shows evidence of renal failure, fluids must be continued, and other medications should be used to stimulate urine production. Some dogs may need peritoneal dialysis, a process where the peritoneum (the membranes surrounding the abdominal organs) is used to filter waste products that are normally filtered by the kidney.

 

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